Date:
Copyright:
de Mattos-Shipley KMJ, Greco C, Heard DM, Hough G, Mulholland NP, Vincent JL, Micklefield J, Simpson TJ, Willis CL, Cox RJ, Bailey AM. The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis. Chem Sci. 2018 Apr 10;9(17):4109-4117. doi: 10.1039/c8sc00717a. PMID: 29780540; PMCID: PMC5941284.
Notes:
Structure of cycloaspeptide B
Images library
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Title
Legend
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1 Axial computed tomography (CT) scans of the frontal sinus.
A: due to the long lasting pressure of mucus, the bone of the anterior wall of frontal sinus is thinned out and elevated anteriorly, forming a bulge. B: same situation as depicted in fig A: the posterior bony wall of frontal sinus is thinned out and extremely elevated posteriorly towards the frontal lobe of the brain. As depicted on the scan, a thin bony layer covering the dura could be recognized intraoperatively
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2 Same patient as 1 and 3, frontal CT
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D. 6 months later, tenacious yellow secretions in L basal bronchial division
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C. After suction the material was seen to extend distally – obstructing the right basal stem bronchus
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B. After suction the material was seen to extend distally – obstructing the right basal stem bronchus
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A. Necrotic mass prolapsing in and out of the distal right intermediate bronchus obscuring both the basal stem and basal division
