Date: 26 November 2013
22/09/08 This chest radiograph shows bilateral hazy diffuse airspace disease predominating in the lower lungs with subtle nodularity in upper zones.
Copyright: n/a
Notes:
A 33 year old known Chronic Granulomatous Disorder (CGD) male presented to A&E in respiratory distress and admitted with severe bibasal pneumonia. He had been laying mulch in his garden. He had not been taking any prophylactic antifungal agents. Oxygen therapy was commenced in conjunction with IV bacterial and fungal treatment with Amphotericin B (Fungizone ®). Further consultation and an adverse reaction to the administration of Fungizone ® led to a switch to IV Voriconazole 300mg BD. The patient tested positive for aspergillus antibodies in serum. The patient declined a bronchoscopy, responded well to IV voriconazole and was discharged home 2 weeks post admission on maintenance voriconazole.
Images library
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Clothing spreads Aspergillus spores – Scanning electron micrograph of Aspergillus niger spores on cotton fibres.
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Clothing spreads Aspergillus spores – Scanning electron micrograph of Aspergillus niger spores on wool fibres.
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A Colonies on MEA after one week;B conidial heads and tip of conidiophore, x 230; C conidial head, x920; E conidial head, x920. Copyright B.Flannigan, R Samson & JD Miller (From Microorganisms in home and indoor work environments, Published by Taylor and Francis)
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3 yr old boy with CNS aspergillosis pt TS. Scan 6 weeks post treatment.
