Images kindly donated by Frank-Michael C. Müller, Pediatric Pulmonology, Cystic Fibrosis Centre and Infectious Diseases, Department of Pediatrics III, University of Heidelberg, Im Neuenheimer Feld 430, D-69120 Heidelberg, Germany.
Notes:
Confocal scanning laser microscopy – (CLSM). CAAF stained showing the hyphal network in contact with extracellular matrix. The polysaccharides of the ECM and fungal cell walls were stained by CAAF (concanavalin A-Alexa Fluor 488 conjugate).
Side effects of anti-fungal drugs – drug rashes. Patient PW: Amphotericin B rash. Livido reticularis – type rash on the knees, associated with amphotericin B deoxycholate treatment, which resolved after discontinuing therapy.