Description:
Candida albicans is one of the fungal species most commonly causing life threatening infections in vulnerable patients. Our group is studying the mitochondria in Candida albicans cells.
Just like in our cells the mitochondria are the batteries of the cell, producing energy required for growth and in fungal cells can also influence infection.
The mitochondria can influence components of the fungal cell wall and its ability to infect us.
If we understand how mitochondria are influencing these factors, we can develop new anti-fungals or we can use existing anti-fungals in new combinations in order to tackle life threatening infections.
Lucian Duvenage works in Dr Campbell Gourlay’s lab at the University of Kent
Medical and Patient education videos
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Title
Description
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Powerpoint presentation December 2009
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Published on 23 Apr 2014.
Wild Type A. fumigatus strain differences and antifungal susceptibility in Invasive Pulmonary Aspergillosis
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Published on 18 Jun 2014 CT scan image of a dog with Nasal Aspergillosis
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Uploaded on 11 Feb 2012 Dr. Sunena Argo discusses the diagnosis and management of ABPA
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Uploaded on 12 Feb 2012 Dr. Heather Doss reviews the diagnosis and management of ABPA. Held on Oct 17, 2011.
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Published on 28 Dec 2012 Developed and produced for http://www.MechanismsinMedicine.com Animation Description: One of the most lethal complications of invasive aspergillosis is dissemination to the brain. The diagnosis is difficult and it has been associated with near 100% mortality, however aggressive antifungal therapy can improve outcomes. Watch this animation for more information.
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“With every breath you take, you are inhaling a potentially deadly pathogen. You can’t see this parasite floating into your nostrils and weaving its way down into your lungs. You probably breathe many of them right back out again, but some stick with every breath. If you’re a healthy non-smoker, have no fear, your immune system has an excellent chance of destroying the invaders before they can make you sick. If your lungs or immune system are compromised, you still have an excellent chance of escaping these frequent attacks unscathed. But, for the unlucky few among us, the fungal pathogen Aspergillus might just win. Let’s take a closer look and see what we could be in for.”
An online science educational resource – intended for students but is suitable for the layperson.
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