A Lys-EGFP mouse was treated as described for movie 4. The sequence shows highly active neutrophils (green) migrating through the lung tissue (blue) either carrying engulfed conidia (light blue) or being caught in the act of phagocytosis. Nuclei and NETs in the area are stained red (Sytox Orange). The average velocity of neutrophils in this experiment was 9.8 µm/min and 54% of cells were migrating at any time point (activity). Indicated is a scale bar and real time in minutes.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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An interesting description of how a skin prick test is carried out with the intention of finding out which substances a patient is allergic to. Amongst other substances Aspergillus is tested for in this video.
This type of test is quick and easy to carry out and can be useful when screening a large number of allergens. More detailed description
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The CF Discovery SeriesTM is an informative and engaging program designed to educate and uplift those with cystic fibrosis. Through interactive presentations with experts in the field, those living with cystic fibrosis gain information in a setting which encourages camaraderie and community. You can attend these events in person. Guests attending in person must follow CFRI’s Infection Control Policy, found here.
