A Lys-EGFP mouse was infected with swollen A. fumigatus conidia and 7 h later the lung was prepared as described in movie 3. The sequence shows several neutrophils (green) migrating within lung tissue (blue). Red staining is from the DNA-specific dye Sytox Orange showing cell nuclei cut open by the preparation. Please note the active motility of cells within the tissue. Indicated is a scale bar and real time in minutes.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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Prof. Neil Gow, University of Aberdeen
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Chair: Prof. Peter Donnelly
Proposers: Drs. Keith Wilson (BMT Unit, Cardiff) & Vanya Gant (Microbiology, UCLH, London)
Opposers: Drs. Brian Jones (Microbiology, Glasgow) & Stephen Ellis (Imaging, Barts, London) -
Dr. Jonathan Lambourne, Hospital for Tropical Diseases, London
Dr. Subathira Dakshina, Genito-Urinary Medicine & HIV, Bart’s Health NHS Trust, London -
Prof. Paul Verweij, Microbiology, Nijmegen, The Netherlands
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Dr. Gemma Johnson & Prof. Stephen Bustin, Anglia Ruskin University, Chelmsford
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Dr. Chris Thornton, University of Exeter
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Prof. Rosemary Barnes, Cardiff University School of Medicine
Dr. Mansour Ceesay, King’s College Hospital, London -
An annual clinical forum intended to provide updates on a wide range of fungal infection topics
http://fungalupdate.org/
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Prof. David Denning, Professor of Infectious Diseases in Global Health, The University of Manchester
