A Lys-EGFP mouse was infected with swollen A. fumigatus conidia and 7 h later the lung was prepared as described in movie 3. The sequence shows several neutrophils (green) migrating within lung tissue (blue). Red staining is from the DNA-specific dye Sytox Orange showing cell nuclei cut open by the preparation. Please note the active motility of cells within the tissue. Indicated is a scale bar and real time in minutes.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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Prof. Neil Gow, University of Aberdeen, Fungal update 2015, 10th Anniversary
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Dr. Elaine Bignell, University of Manchester, Fungal Update 2015, 10th Anniversary
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Prof. Rob Miller, University College London, Funagl Update 2015, 10th Anniversary
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Prof. Tom Harrison, St George’s University Hospitals, London, Fungal Update 2015, 10th Anniversary
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Chair: Prof. Peter Donnelly
Proposers: Drs. Keith Wilson (BMT Unit, Cardiff) & Vanya Gant (Microbiology, UCLH, London)
Opposers: Drs. Brian Jones (Microbiology, Glasgow) & Stephen Ellis (Imaging, Barts, London)Debate – Fungal Update 2015, 10th Anniversary
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Dr. Jonathan Lambourne, Hospital for Tropical Diseases, London, Fungal Update 2015, 10th Anniversary
Dr. Subathira Dakshina, Genito-Urinary Medicine & HIV, Bart’s Health NHS Trust, London, Fungal Update 2015, 10th Anniversary
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Prof. Maiken Arendrup, Statens Serum Institut, Denmark, Funal Update 2015, 10th Anniversary
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Prof Chris Kibbler, University College London, Fungal Update 2015, 10th Anniversary
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Dr. Frank van de Veerdonk, Nijmegen, The Netherlands
