A Lys-EGFP mouse was infected with swollen A. fumigatus conidia and 7 h later the lung was prepared as described in movie 3. The sequence shows several neutrophils (green) migrating within lung tissue (blue). Red staining is from the DNA-specific dye Sytox Orange showing cell nuclei cut open by the preparation. Please note the active motility of cells within the tissue. Indicated is a scale bar and real time in minutes.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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Nasal Aspergillosis destroys the bone in and around the nose. Unfortunately this case could not be treated and the dog had to be euthanised.
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Nasal aspergillosis with moderate turbinate destruction and fungal plate on left frontal sinus mucosa. Biopsy was performed and 10% clotrimazole cream was applied through endoscope.
[Aspergilosis nasal con moderada destrucción de cornete etmoidal izquierdo y placa micótica sobre mucosa de seno frontal. Se realizó la biopsia y se aplicó una crema de clotrimazol al 10% mediante el endoscopio.]
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This video depicts removal of superficial fungal infection involving the right ear canal by using suctioning technique
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More examination & analysis of lung specimens from a patient with aspergillosis
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A histological tour of the signs of aspergillosis in lung specimens
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A collection of short video’s hosted by the Aspergillus Website showing various aspects of the cell biology of Aspergillus and how parts of our immune system fights the infection.
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Sir David Attenborough and the Planet Earth team discover the weird world of the Cordyceps; killer fungi that invades the body of an insect to grow and diminish the insect population. Fascinating animal and wildlife video from the BBC epic natural world masterpiece ‘Planet Earth’.
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This video was kindly provided with permission from Lariontsev Nikolay.
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A patient describes her experience of living with chronic pulmonary aspergillosis and treatment with itraconazole.
