A Lys-EGFP mouse was infected with swollen A. fumigatus conidia and 7 h later the lung was prepared as described in movie 3. The sequence shows several neutrophils (green) migrating within lung tissue (blue). Red staining is from the DNA-specific dye Sytox Orange showing cell nuclei cut open by the preparation. Please note the active motility of cells within the tissue. Indicated is a scale bar and real time in minutes.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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Nasal aspergillosis in 8 years old dog with sneezing, reverse sneezing and epistaxis. After rhinoscopy the nasal cavity was flooded with 10% enilconazole solution during 60 min. We had to change the type of scope to clean the fungal plaque over the caudal recess of the right frontal sinus.
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Published on 31 Jan 2015 Dr Gemma Johnson, Public Health England
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Published on 10 Jul 2014.
Patient information video outlining the role of antibody testing in the management of Aspergillosis
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Published on 2 Nov 2013.
Gasping is a typical sign of aspergillosis in chicks.
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Published on 4 Apr 2013.
Placa micótica sobre cornete etmoidal con destrucción de turbinado. Perra mestiza de 9 años de edad con descarga nasal unilateral muco-sanguinolenta.
[Mycotic plate on ethmoid turbinate with tissue destruction. Bitch, 9 years old, nasal unilateral discharge.]
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Published on 27 May 2013.
Paper presented at the Annual Meeting of the Lebanese Pulmonary Society – Mövenpick Hotel – April 24th to 27th, 2013 – Beirut – Lebanon Conférence présentée lors du Congrès annuel de la Société Libanaise de Pneumologie – Hôtel Mövenpick – 24 au 27 avril 2013 – Beyrouth – Liban
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Moffe is a dog that got well from Nasal Aspergillosis. He is a collie, born with a brain damage, as has been documented with cerebral CT scan, he is blind at one eye and deaf at one ear, he is scared of strange places and slippery floors, and is skinny with poor appetite. When he was 7 years old, he was diagnosed with gingivitis and nasal Aspergillosis. According to scientific papers, Aspergillosis is hard to treat, and the veterinaries strongly recommended euthanasia. However, a dentist veterinarian proposed to try to retract some teeth. After this, he recovered. He did not receive any treatment for the Aspergillosis besides retraction of teeth. Now, more than two years ago, he has not had any more problems with his nose or his teeth. I hope this information could be of interest to other owners of dogs with Aspergillosis.
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Fighting the agile aspergillosis by David Denning
