A Lys-EGFP mouse was infected with swollen A. fumigatus conidia and 7 h later the lung was prepared as described in movie 3. The sequence shows several neutrophils (green) migrating within lung tissue (blue). Red staining is from the DNA-specific dye Sytox Orange showing cell nuclei cut open by the preparation. Please note the active motility of cells within the tissue. Indicated is a scale bar and real time in minutes.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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Vicky Barber introduces the British Lung Foundation to patients
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Jeanette Boyd introduces the Eurpoean Lung Foundation (ELF) to patients
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Dr. Stuart Levitz discusses animal research, antifungal vaccines and boosting the immune system, plus Q & A with patients
