Isolated neutrophils were incubated together with hyphae in the presence of the blue DNA dye Hoechst in a laboratory made incubation chamber and analysed by live cell microscopy. The movie shows how a number of free neutrophils associate with a small hyphal fragment and transport it to an area, where a larger hypha is already associated with many other neutrophils. Similar phenomena can be observed in acute lung slices. Real time is given at the bottom of the movie.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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European Respiratory Society: Current thinking regarding the importance of nutritional science in the management and prevention of COPD.
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European Respiratory Society: Should we be testing new drugs in the ‘real’ world where some patients smoke, are obese and have other comorbidities?
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European Respiratory Society: A revolutionary collaborative approach to research funding is providing new insights into the origins of chronic respiratory diseases.
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European Respiratory Society: Clean air is vitally important for people who live with aspergillosis. Chemical pollutants have the capacity to worsen symptoms and quality of life, PM2.5 particulates (mentioned in this video) include aspergillus and other fungal spores.
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European Respiratory Society launches its latest vision to support those with respiratory health difficulties throughout europe: encouraging patients to increase their levels of activity which is proven to improve lung health.
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Stewart Armstrong inspiring many people to do ‘Push-ups for aspergillosis’ to raise awareness and funds for aspergillosis research.
Facebook page (November 2015)
Also see the compelling video of Stewarts’ story as told by himself
