Isolated neutrophils were incubated together with hyphae in the presence of the blue DNA dye Hoechst in a laboratory made incubation chamber and analysed by live cell microscopy. The movie shows how a number of free neutrophils associate with a small hyphal fragment and transport it to an area, where a larger hypha is already associated with many other neutrophils. Similar phenomena can be observed in acute lung slices. Real time is given at the bottom of the movie.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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Fungi are eukaryotic organisms which possess a unique cell wall and cell membrane that can serve as targets for antifungal agents. The echinocandin class of antifungal agents target the cell wall of fungi. Watch this animation for more information.
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Fungi are eukaryotic organisms which possess a unique cell wall and cell membrane that can serve as targets for antifungal agents. Polyene antifungal agents such as Amphotericin B target the fungal cell membrane. Watch this animation for more information.
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Fungi are eukaryotic organisms and are not related to bacteria. As eukaryotes, they contain membrane bound organelles and possess a cell membrane surrounded by a rigid cell wall. Watch this animation for more information on the unique structural properties of fungi.
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A review of antifungals, focusing on amphotericin B, azoles, and echinocandins. Structure, mechanism, spectrum of antifungal activity, common clinical uses, and common side effects/toxicities are all discussed. (April 2015)
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Fungi are eukaryotic organisms which possess a unique cell wall and cell membrane that can serve as targets for antifungal agents. Polyene antifungal agents such as Amphotericin B target the fungal cell membrane.
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Fungi are eukaryotic organisms which possess a unique cell wall and cell membrane that can serve as targets for antifungal agents. Polyene antifungal agents such as Amphotericin B target the fungal cell membrane.
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Healthy Buildings 2015 Europe – Eindhoven, The Netherlands
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Healthy Buildings 2015 Europe – Eindhoven, The Netherlands
