After 180 minutes of neutrophil-Aspergillus co-incubation a well established NET is visible. At the beginning of the movie (0 min) DNase I was added to the medium. At 7 minutes digestion of the NET started and was finished (no NET structure detectable) by 9.5 minutes into the experiment. Indicated is a scale bar and real time in minutes.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.http://www.plospathogens.org/article/…
Medical and Patient education videos
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Title
Description
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Fungal infections are an integral part of Infectious Diseases but they are increasingly seen in all specialities. The University of Manchester Medical Mycology taught Masters programme has been designed to provide a significant level of theoretical understanding and practical skills in the field of fungal infectious diseases.
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Professor Denning talks about GAFFI at the London launch of the foundation, in the House of Commons. GAFFI is the global action fund for fighting fungal infections.
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This a longer (3.52) version of a film produced by GAFFI, ,Global Action Fund for Fungal Infections (gaffi.org) to highlight the dangers of fungal Infections worldwide and a call for more research and access to anti-fungal medicines and testing. The film was produced to mark the first year of activities by GAFFI.
