Interview with CPA patient RW on long term antifungal treatments

Group: Patients and general interest

Description:

A patient interview. This patient RW- with long term chronic pulmonary aspergillosis describes his experiences over 18 years during which he has taken various antifungal treatments. He remains well and currently takes itraconazole. A synopsis is shown below. This patient underwent a lung resection in 1991 for a suspect lesion in his lung, histology revealed inflammation and an area containing fungal hyphae consistent with a fungal ball. Resection appeared to cure the problem. However in 1992 he re-presented with a large new cavity near the site of the surgery and a probable fungal ball seen on X ray. A bronchoscopy sample grew aspergillus and his blood tests were positive for aspergillus precipitins. Chronic pulmonary aspergillosis was diagnosed. Antifungal treatment on itraconazole was started and much improvement was seen. During the next few years the patient tried voriconazole (as a trial drug) – on which he experienced a red facial rash; IV amphotericin – which improved his condition markedly. Itraconazole treatment was then restarted and the patient has been largely stable on this antifungal drug over the last 13 years. On the occasions he has stopped the drug – he has relapsed and it has taken some months before he was again stable. The patient is currently in good health (11/09). We would like to thank the patient for agreeing to share his experiences.


Medical and Patient education videos

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  • I have Sarcoidosis, Chronic Pulmonary Aspergillosis (CPA) and a very low CD4 count. I have challenged myself to do a daily vlog for 30 days

    Follow me on twitter @StewArmstrong

    Here is the link for all of the monthly aspergillosis meetings http://www.nacpatients.org.uk/monthly… 

    This meeting was for July 2016.

    Aspergillus Website: Follow all of our Youtube collections here

  • Stewart Armstrong has chronic pulmonary aspergillosis and has undertaken to record a video of every day of his life for a month in order to help raise awareness of aspergillosis and how it impacts their daily lives.

    These videos are interesting for a number of reasons – not least because patients often say that they don’t look unwell so many people don’t understand how serious aspergillosis is. Does Stewart look or act unwell?

    See the month of vlogs in the playlist below, or go to Stewart’s YouTube page to watch more of his videos.

  • Global fungal killers and life-threatening infections

    Fungi are everywhere, and a few species can cause very serious lethal infections. Fungal infections 

    See exhibition webpage

  • This panel considers and debates one of the greatest obstacles to food security in many parts of the world: mycotoxin. Aflatoxin is a particularly dangerous mycotoxin produced predominantly by two Aspergillus fungi. It colonizes a variety of important food and feed crops both pre- and post-harvest, including groundnuts, tree nuts, maize, rice, figs and other dried foods, spices, crude vegetable oils and cocoa. Contaminated crops have significant health risks for both humans and animals, having been linked to retarded growth and development (stunting), immunosuppression and liver cancer. The aflatoxin issue has other, complex implications for food security and, by limiting farmers’ access to international markets, can lead to food waste and economic instability.

    Panelists: 
    -John Lamb, Principal Associate, Abt Associates
    -Dr. Kitty Cardwell, National Program Leader, USDA-NIFA
    -Barbara Stinson, Senior Partner, Meridian Institute; Project Director, Partnership for Aflatoxin Control in Africa
    -Moderator: Dr. Howard-Yana Shapiro, Chief Agricultural Officer, Mars, Incorporated

  • The role of poorly maintained ventilation ductwork in spreading airborne infections is largely ignored because it is ‘out of sight out of mind’, but recent analysis by healthcare professionals confirms that the risks are increasing.

    Ghasson Shabha will identify particular threats in healthcare facilities from dirty ductwork. He also points out that fewer than 5% of building air-conditioning systems have been inspected despite regulations making this mandatory. Dr Shabha will look at how planned cleaning strategies can reduce risks and how hospitals can use 3D building information modelling software to identify ‘infection hotspots’.

    The healthcare environment can be described as a reservoir for potentially infective agents which can spread unpredictably in a whole array of ways particularly in ventilation and air-conditioning systems making it difficult to effectively control and manage, for those seeking timely information about the patterns of cross-infection. The severity of the problem has been highlighted extensively over the past decade, as part of wider umbrella of what was known as health care acquired infections (HCAIs). Airborne transmission extends over a wide spectrum, and includes many prevalent agents, inter alia Mycobacterium tuberculosis (TB),nosocomial MRSA, Aspergillus fumigatus, Serratia marcescens, norovirus, and other airborne infection.

    Dr Shabha was speaking live from Birmingham and this CIBSE ASHRAE Group (cibseashrae.org) webinar was co-sponsored by the B&ES Ventilation Hygiene Group and the Institute of Healthcare Engineering and Estate Management (IHEEM).

  • Oliphant Science Awards – Year 1 project by Haruki Kurioka, Aleksa Novakovic and Bogdan Novakovic (St Andrew’s Primary School, Adelaide)
    Food that we consume daily is rich in good bacteria and fungi. Yogurt, Yakult and Natto (fermented soybeans) are rich in bacteria. Cheeses (e.g. Brie & Blue cheese) and Koji contain fungi Penicillium and Aspergillus, respectively. Many Japanese and continental seasonings and dishes can be prepared with those products. Many kids and their parents don’t know much about good bacteria and fungi. First year students are here to tell us their story. Enjoy it!