Interview with CPA patient RW on long term antifungal treatments

Group: Patients and general interest

Description:

A patient interview. This patient RW- with long term chronic pulmonary aspergillosis describes his experiences over 18 years during which he has taken various antifungal treatments. He remains well and currently takes itraconazole. A synopsis is shown below. This patient underwent a lung resection in 1991 for a suspect lesion in his lung, histology revealed inflammation and an area containing fungal hyphae consistent with a fungal ball. Resection appeared to cure the problem. However in 1992 he re-presented with a large new cavity near the site of the surgery and a probable fungal ball seen on X ray. A bronchoscopy sample grew aspergillus and his blood tests were positive for aspergillus precipitins. Chronic pulmonary aspergillosis was diagnosed. Antifungal treatment on itraconazole was started and much improvement was seen. During the next few years the patient tried voriconazole (as a trial drug) – on which he experienced a red facial rash; IV amphotericin – which improved his condition markedly. Itraconazole treatment was then restarted and the patient has been largely stable on this antifungal drug over the last 13 years. On the occasions he has stopped the drug – he has relapsed and it has taken some months before he was again stable. The patient is currently in good health (11/09). We would like to thank the patient for agreeing to share his experiences.


Medical and Patient education videos

Showing 10 posts of 266 posts found.
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  • Vascular coffee wilt or tracheomycosis is threatening the Ugandan coffee crop as it spreads from neighbouring Democratic Republic of Congo and infects more coffee producing regions. Also in Uganda, making money from honey. Plus, a report from Hong Kong on the World Bank meeting calling for more sustainable farming and how that will affect its lending.

    Coffee Fungus Spreads into Uganda

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  • Ecologist Lynne Boddy tells Bridget Kendall how fungi fight each other for resources and use “chemical warfare” to gain the upper hand.

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  • Put any prejudices about poisonous toadstools and mould in damp corners out of your mind: this week’s Forum explores fungi as an extraordinarily tough and ecologically friendly building substance that could reshape our world. Plus the hundreds of thousands of species of fungi that have yet to be named and studied: some of them may hold vital clues on how to cure diseases or solve environmental problems. Bridget Kendall is joined by fungal ecologist Lynne Boddy, Danish mycologist and photographer Jens Petersen, and San Francisco-based artist, chef and fungal furniture-maker, Phil Ross. Above photo: Hygrocybe Psittacina Photo: © Jens H. Petersen. Below clip photo: Mycelium with Hyphal Strings

    The Mysterious Kingdom of Fungi

    BBC Radio 4 2013

  • Fungi are responsible for rotting fruit, crumbling brickwork and athlete’s foot. They have a mouldy reputation; but it’s their ability to destroy things that enables new life to grow. 90% of all plants depend on fungi to extract vital nutrients from the soil. And it’s probably thanks to fungi that the first plants were able to colonize land 450 million years ago. Professor Lynne Boddy shares her passion for fungi with Jim Al-Khalili and describes some of the vicious strategies they use to defend their territory. Direct strangulation and chemical weapons; it’s all happening underground.

    Lynne Boddy on Fungi

    BBC Radio 4 2016

  • Chris Sperring and Michael Jordan of the Association of British Fungus Groups go in search of giant bracket fungus in Dommett Wood in Somerset.

    Bracket fungus grow on a variety of native trees. The vegetative part of the fungus, known as mycelium, grows under the bark of fallen wood or living trees, and will eventually break down and rot the host tree. However, the part that can most easily be seen is the fruiting body of bracket fungus. These fruiting bodies, growing on tree trunks and fallen logs, allow the fungus to reproduce and exist to produce and liberate millions of microscopic spores.

    In Search of Giant Fungus

    BBC Radio 4 2015

  • Scientist are unable to classify fungi as either plant or animal. They are just as likely to kill you as they are to feed you and their origins are difficult to trace.

    Fungi – Plant or Animal?

  • Fungi Exploitation
    Science is going back to basics …We look at how more than 28,000 strains of fungus held in the UK’s national collection are becoming the focus of research seeking new antibacterial drugs. The collection has great roots – it still holds an original sample of Sir Alexander Fleming’s penicillin. Quentin Cooper is joined by Dr Joan Kelley, Executive Director Bioservices, CABI and Professor Peter Bramley, Head of the School of Biological Sciences Royal Holloway, University of London.

    Fungi Exploitation – Electron Microscopes

    February 2008 BBC Radio 4

  • Dr. Samir Agrawal, Barts Health NHS Trust, London, Fungal Update 2015, 10th Anniversary 

  • Dr. Frank van de Veerdonk, Nijmegen, The Netherlands, Fungal update 2015, 10th Anniversary