Nidulin

ID 2: 400

Toxin: n

Trivial name:

11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​(1-​methyl-​1-​propenyl)​-​, (E)​-; 11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​(1-​methylpropenyl)​- (8CI); 11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​[(1E)​-​1-​methyl-​1-​propenyl]​- (9CI); Nidulin (6CI,​7CI); 4,​2-​Cresotic acid, 3,​5-​dichloro-​6-​[5-​chloro-​2-​hydroxy-​4-​methoxy-​6-​(1-​methylpropenyl)​-​m-​tolyloxy]​-​, ε-​lactone

Systematic name:

11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​[(1E)​-​1-​methyl-​1-​propen-​1-​yl]​-

Molecular formulae: 

C₂₀H₁₇Cl₃O₅

Molecular weight: 443.70

Chemical abstract number: 10089-10-8

Literature reference:

• Nidulin and ustin-​two chlorine-​containing metabolic products of Aspergillus nidulans. Dean, F. M.; Robertson, A.; Roberts, John C.; Raper, K. B. Nature (London, United Kingdom) (1953), 172, 344.
  Studies on fungal products. XVIII. Isolation and structures of a new fungal depsidone related to nidulin and a new phthalide from Emericella unguis. Kawahara, Nobuo; Nakajima, Shoichi; Satoh, Yumiko; Yamazaki, Mikio; Kawai, Kenichi. Chemical & Pharmaceutical Bulletin (1988), 36(6), 1970-5.

References URL: 

• http://pubchem.ncbi.nlm.nih.gov/substance/53213552
• http://www.nature.com/nature/journal/v172/n4373/abs/172344a0.html
• https://www.jstage.jst.go.jp/article/cpb1958/36/6/36_6_1970/_article

Aspergillus Species known to produce this metabolite:

• /species/a-nidulans
• /species/emericella-unguis

Date uploaded: 2008-07-07 16:58:01

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Mycotoxin & Metabolites

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