Mellein/ Ochracin

ID 2: 118

Toxin: n

Trivial name:

1H-​2-​Benzopyran-​1-​one, 3,​4-​dihydro-​8-​hydroxy-​3-​methyl-​, (R)​-; Isocoumarin, 3,​4-​dihydro-​8-​hydroxy-​3-​methyl-​, (R)​-​(-​)​- (8CI); (-​)​-​(R)​-​Mellein; (-​)​-​Mellein; (3R)​-​Mellein; (R)​-​(-​)​-​Mellein; (R)​-​3,​4-​Dihydro-​8-​hydroxy-​3-​methyl-​1H-​2-​benzopyran-​1-​one; (R)​-​Mellein; Mellein; Ochracin

Systematic name:

1H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-methyl-, (3R)-

Molecular formulae: 

C₁₀H₁₀O₃

Molecular weight: 178.18

Chemical abstract number: 480-33-1

Literature reference:

• Ochracin, a new metabolic product of Aspergillus ochraceus. Yabuta, Teijiro; Sumiki, Yusuke. Nippon Nogei Kagaku Kaishi (1933), 9, 1264-75.
  Biochemisty of molds. II. A metabolic product of Aspergillus melleus Yukawa. Nishikawa, Eijiro. Nippon Nogei Kagaku Kaishi (1933), 9, 772-4.
  New metabolic products of Aspergillus flavus. I. Asperentin, its methyl ethers, and 5′-​hydroxyasperentin. Grove, John Frederick. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1972), (19), 2400-6.

References URL: 

• http://pubchem.ncbi.nlm.nih.gov/substance/162222558
• https://www.jstage.jst.go.jp/article/nogeikagaku1924/9/11/9_11_1264/_article/-char/ja/
• https://www.jstage.jst.go.jp/article/nogeikagaku1924/9/8/9_8_772/_article/-char/ja/
• http://pubs.rsc.org/en/Content/ArticleLanding/1972/P1/p19720002400#!divAbstract

Aspergillus Species known to produce this metabolite:

• /species/a-ochraceus
• /species/a-melleus
• /species/a-flavus

Date uploaded: 2008-07-07 16:58:01

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Mycotoxin & Metabolites

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Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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