Gliotoxin G (2)

ID 2: 246

Toxin: n

Trivial name:

2,​3,​4,​5-​Tetrathia-​7,​9-​diazabicyclo[4.2.2]​decane-​8,​10-​dione, 7,​9-​bis(methoxymethyl)​-​1,​6-​bis(phenylmethyl)​-​, (±)​-

Systematic name:

2,3,4,5-Tetrathia-7,9-diazabicyclo[4.2.2]decane-8,10-dione, 7,9-bis(methoxymethyl)-1,6-bis(phenylmethyl)-

Molecular formulae: 

C₂₂H₂₄N₂O₄S₄

Molecular weight: 508.70

Chemical abstract number: 87869-02-1

Literature reference:

• Structure and synthesis of cis-​3,​6-​dibenzyl-​3,​6-​bis(methylthio)​piperazine-​2,​5-​dione, a new metabolite of Aspergillus terreus. Kirby, Gordon W.; Robins, David J.; Stark, W. Marshall. Journal of the Chemical Society, Chemical Communications (1983), (15), 812-13.
  Partial synthesis of gliotoxin G, an epitetrathiodioxopiperazine. Kirby, Gordon W.; Rao, Ghanakota V.; Robins, David J.; Stark, W. Marshall. Tetrahedron Letters (1986), 27(45), 5539-40.

References URL: 

• http://pubs.rsc.org/en/Content/ArticleLanding/1983/C3/c39830000812#!divAbstract
• http://www.sciencedirect.com/science/article/pii/S0040403900852612

Aspergillus Species known to produce this metabolite:

• /species/a-fumigatus
• /species/a-terreus

Date uploaded: 2008-07-07 16:30:55

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Mycotoxin & Metabolites

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