Butyrolactone I

ID 2: 233

Toxin: n

Trivial name:

Butyrolactone I
Olomoucin

Systematic name:

2-Furancarboxylic acid, 2,5-dihydro-4-hydroxy-2-[[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxo-, methyl ester, (2R)-

Molecular formulae: 

C₂₄H₂₄O₇

 

Molecular weight: 424.4

Chemical abstract number: 87414-49-1

Literature reference:

• Studies on the metabolic products of Aspergillus terreus. III. Metabolites of the strain IFO 8835. (1). Kiriyama, Noriki; Nitta, Keiichi; Sakaguchi, Yoshiaki; Taguchi, Yasuhisa; Yamamoto, Yuzuru. Chemical & Pharmaceutical Bulletin (1977), 25(10), 2593-601.
  Cancer and cell cycle inhibitor. A specific inhibitor for cdc2 family kinase. Kitagawa, Masatoshi; Nishimura, Susumu. Saishin Igaku (1993), 48(3), 418-24.

References URL: 

• http://pubchem.ncbi.nlm.nih.gov/substance/135078959
• https://www.jstage.jst.go.jp/article/cpb1958/25/10/25_10_2593/_article

Aspergillus Species known to produce this metabolite:

• /species/a-terreus

Toxicity:

Cell cycle inhibitor

Date uploaded: 2008-07-07 15:48:31

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Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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