Austalide I

Systematic name:

5H-​Furo[3,​4-​i]​oxepino[4,​3-​a]​xanthene-​3,​12-​dione, 6-​(acetyloxy)​-​1,​2,​5a,​6,​7,​7a,​10,​14,​14a,​14b-​decahydro-​13-​methoxy-​5,​5,​7a,​9,​14b-​pentamethyl-​, (5aS,​6R,​7aS,​14aR,​14bR)​- (9CI)

Molecular formulae: 

C₂₇H₃₄O₈

Molecular weight: 486.6

Chemical abstract number: 96817-08-2

Literature reference:

• Metabolites of Aspergillus ustus. Part 1. Application of the heteronuclear selective population inversion (SPI) NMR technique to the structure elucidation of the austalides A-​F, novel ortho ester meroterpenoids. Horak, R. Marthinus; Steyn, Pieter S.; Vleggaar, Robert; Rabie, Christiaan J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1985), (2), 345-56.
  Metabolites of Aspergillus ustus. Part 3. Structure elucidation of austalides G-​L. Horak, R. Marthinus; Steyn, Pieter S.; Vleggaar, Robert; Rabie, Christiaan J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1985), (2), 363-7.
  Metabolites of Aspergillus ustus. Part 4. Stable-​isotope labeling studies on the biosynthesis of the austalides. De Jesus, Amelia E.; Horak, R. Marthinus; Steyn, Pieter S.; Vleggaar, Robert. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1987), (10), 2253-7.

References URL: 

• http://pubs.rsc.org/en/Content/ArticleLanding/1985/P1/p19850000363#!divAbstract
• http://pubs.rsc.org/en/Content/ArticleLanding/1985/P1/p19850000345#!divAbstract
• http://pubs.rsc.org/en/Content/ArticleLanding/1987/P1/p19870002253#!divAbstract
• https://drugs.ncats.io/drug/SO7S6DS7TQ

Aspergillus Species known to produce this metabolite:

• /species/a-ustus

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Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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