Study of aero-allergen sensitization in subjects with naso-bronchial allergy in a tertiary care centre from India

Author:

Vijayasarathi MK 1; Santosh KM 2; Sapare AK 3; Manjunath PH 1; Tousheed SZ 2; Muralimohan BV 3; Raykar P 1; Hemanth Kumar M 2

Author address:

1 Narayana Hrudayalaya, Bangalore, India; 2 Mazumdar Shaw Hospital, Bangalore, India; 3 Bommasandra, Bangalore, India

Full conference title:

European Academy of Allergy and Clinical Immunology Congress 2017

Date: 20 August 2020

Abstract:

Introduction: To study the pattern of allergen sensitization in patients with allergic rhinitis and asthma.

Objectives: We have analyzed retrospective data of 580 patients who underwent skin prick test for nasobronchial allergic symptoms at Narayana Hrudayalaya Hospital, Bangalore between June 2014 and March 2017. Ethical approval from the institutional committee was obtained. Data analyzed include, history, skin prick data and clinical examination details. Conditions were classified according to GINA (for asthma) and ARIA (for allergic rhinitis) guidelines. Skin prick test was performed using standardized allergens.

Results: Out of 580 patients, 338 (58.3%) were males. The male to female ratio was 1:1.4. The mean age was 23.9  14.2 years. Fifty seven percent of patients were above 18 years of age and 43.1% were below 18 years. Allergic rhinitis (AR) and bronchial asthma (BA) was almost equally presented in patients (88.4% vs 88.3% respectively). Seventy-two percent of patients presented with both AR and BA. Family history of allergy was positive in 67.1%. Seventy-nine percent of patients were positive for at least one allergen tested and 42% had more than one sensitization (table 1). Sensitization was more in men than women. There was a positive co-relation between number of allergen sensitization and increasing age (P=.041).

Conclusions: Prevalence of sensitization was 79% in patients with nasobronchial allergy. The most common allergen being House dust mite mix (Dermatophagoides pteronyssinus and Dermatophagoides farinae) at 66.9%. The next most prevalent allergen is cockroach allergen at 47.2%. The prevalence of fungal and pollen sensitization were relatively low at 11% and 8.7% respectively. We present one of the largest data from India on pattern of allergen sensitization. The prevalence and incidence of allergy is rapidly growing in India, but the data remains scarce. To address the geographical differences and planning proper treatment strategies require a good descriptive study.

Abstract Number: 1635

Link to conference website:

Link Conference abstract: 

EAACI 2017

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