Ref ID: 18762
Author:
Y. Meije, MD – ID Physician, G. Fresco, MD – ID Physician, P. Martín-Dávila, MD – ID Physician, E. Loza, MD – Microbiologist, E. Gómez-GªPedrosa, MD – Microbiologist, J. Rodríguez, MD – ID Physician, V. Pintado, MD – ID Physician, J. Cobo, MD – ID Ph
Author address:
Hosp. Ramón y Cajal, Madrid, Spain.
Full conference title:
52nd Annual ICAAC
Date: 9 September 2014
Abstract:
Background: Clinical impact of reporting Candida spp. colonized catheters for patients (pt) without fungemia is an unresolved issue defined by IDSA clinical guidelines Methods: This is a retrospective study to analyse demographic data, outcomes and physician decision made about all non candidemic pt with a positive intravascular catheter (IVC) tip for Candida spp. during a 5 years period (2006-20011) in Ramí³n y Cajal tertiary-care hospital. We also compared this cohort with all catheter-related candidemia population during the same period Results: 78 patients had Candida spp. catheter colonization without candidemia. Mean age was 59,65 years. Mean Charlson score was 3,21. Mean time of length hospitalization before positive IVC was 37,76 days. Main Candida sp isolated was C. albicans (60,3%) and C.parapsilosis (21,8%). The most frequent IVC was jugular (37%) follow by femoral (17%). Mean time of antibiotic treatment duration before positive IVC was 16,37 days SD (9,68). Mean Candida score was 1,81 and Pittet Candida colonization index 0,49. 35/78 pt (44,9%) received antifungal treatment, physician decision was made because sepsis and C. score >/= 3 in 23 of them and intravascular device or recent heart surgery in 5 of them. 4 pt developed other invasive Candida infection sites at the same time as the catheter colonization. Among the other 43 pt who didn’t receive treatment no one of them developed candidemia or invasive candidiasis, these all pt were no septic and their Candida score was = 2 When it was compared with 133 pt with catheter-related candidemia, C. parapsilosis IVC colonization and parenteral nutrition were independent risk factors associated with candidemia development in multivariate analysis 8232; Conclusions: IVC Candida spp. colonization is a frequent problem among pt. Pt non septic or with C. score =2 are under a very low risk of candidemia or invasive candidiasis therefore non antifungal treatment for these pt would be considered a good option. Pt with C. parapsilosis IVC colonization or parenteral nutrition may have increased risk of candidemia development
Abstract Number: M-1700
Conference Poster: y
Conference Year: 2012
Link to conference website: NULL
New link: NULL
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