Author:
Shiquan, W; Baoqing, S; Wenting, L; Nili, W
Author address:
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
Full conference title:
European Academy of Allergy and Clinical Immunology Congress 2015
Date: 5 August 2020
Abstract:
Background: Among the patients with serum total immunoglobulin E (TIgE) higher than 1000 ku/L, who suffered from respiratory diseases, we could found the majority of them were sensitized to house dust mite (HDM) and Aspergillosis. We aimed to find out if there any correlation with TIgE among serum specific immunoglobulin- -E (sIgE) against house dust mite along with Aspergillosis in the patients.
Methods: 64 subjects with high level of TIgE were tested for serum sIgE-derp1 and sIgE-Af by using ImmunoCAP 100. Result: Of 68.8% (44/64) patients were sensitive to HDM while 40.6% (29/64) were sensitive to aspergillosis. What’s more, 37.5% (24/64) patients could be detected sIgE (derp1,Af) while 15/64 (23.4%) patients were found sIgE(derp1, Af)-free. 20/64 (31.3%) patients were merely sensitive to HDM while 5/64 (7.8%) were sensitive to Aspergillosis. Among the patients with TIgE higher than 1000ku/L, those patients sensitive to HDM was significantly more than those sensitive to Aspergillosis (ka=9.00,t= P < 0.01). sIgE-Af (r = 0.410) was correlated more with TIgE than sIgE-derp1 (r = 0.228) was (P < 0.05).
Conclusion: Most of the patients with high level of TIgE, complicated with respiratory diseases, were more likely sensitive to HDM rather than Aspergillosis. Compared to sIgE against HDM, sIgE-Af contributed more to the level of TIgE. The detection of sIgE against HDM and Aspergillosis was important for the patients complicated with respiratory and high level of TIgE.
Abstract Number: 1289
Link to conference website:
Link Conference abstract:
Conference abstracts, posters & presentations
-
Title
Author
Year
Number
Poster
-
v
Mrs Ange Brennan (UK)
2024
n/a
-
v
Tianyu Lianga, Nir Osherovb, Ruoyu Lia, Qiqi Wanga, Wei Chena, Zhe Wana, Wei Liua*
2024
n/a
-
v
Jillian Simard, MD,1 Christopher Melani, MD,2
Rahul Lakhotia, MD,1
Michail S. Lionakis, MD
ScD,*,3
Stefania Pittaluga, MD PhD,4
James D. Phelan, PhD,*,1 Jagan R. Muppidi, MD
PhD,*,1
Lydia L. Chou, CRNP,*,1
Matthias Holdhoff, MD PhD,*,5 Michael Glantz, MD PhD,*,6
John A. Butman, MD PhD,*,7 Andrea Nicole Lucas, RN,*,8
Seth M. Steinberg, PhD,*,9
Elaine
S. Jaffe, MD,4
Louis M. Staudt, MD PhD,1
Wyndham H. Wilson, MD PhD,1 Mark Roschewski, MD102020
n/a
-
v
Mark Roschewski, MD,1
Christopher Melani, MD,2
Rahul Lakhotia, MD,3
Stefania Pittaluga, MD
PhD,4
James D. Phelan, PhD,*,3
Cody Peer, PhD,*,5 Michail S. Lionakis, MD ScD,*,6 Lydia
L. Chou, CRNP,*,3 Matthias Holdhoff, MD PhD,*,7 Michael Glantz, MD PhD,*,8 Jan Drappatz, MD,*,9
Catherine Lai, MD MPH,10 John A. Butman, MD PhD,*,11 Andrea Nicole Lucas, RN,*,12 Seth
M. Steinberg, PhD,*,13 William D. Figg, PhD,*,14 Elaine S. Jaffe, MD,4
S. Percy Ivy, MD,*,15
Richard F. Little, MDMPH,16 Louis M. Staudt, MD PhD,3
Wyndham H. Wilson, MD PhD32020
n/a
-
v
Binav Baral, MD,*,1 Prasanth Lingamaneni,*,2 Trilok Shrivastava, MD,*,3 Maryam Zia,4 Ishaan Vohra, MD,*,2
Krishna Rekha Moturi*,32020
903
n/a
-
v
Maxwell Green1, Scout Treadwell1, Geetha Gowda1, John Carlson, MD, PhD2
2023
610
n/a
-
v
Catherine Blackwood, PhD1 , Angela Lemons, MS2 , Rachael Rush3 , Walter McKinney2 , Dori Germolec4 , Donald Beezhold, PhD2 , Brett Green, PhD5 , Tara Croston, PhD6
2023
583
n/a
-
v
Catherine Blackwood, PhD1 , Angela Lemons, MS2 , Rachael Rush3 , Walter McKinney2 , Dori Germolec4 , Donald Beezhold, PhD2 , Brett Green, PhD5 , Tara Croston, PhD6
2023
583
n/a
-
v
Jennifer Roper, MD1, Sebastian Ochoa, MD2, Anahita
Agharahimi, MSN, CRNP2, Justina Pfister, RN2, Magdalena
Walkiewicz, PhD2, Amanda Urban, DNP, CRNP3, Rajarshi
Ghosh, PhD2, Michail Lionakis, MD, ScD2, Lisa Kohn, MD, PhD4, Kenneth Olivier, MD, MPH2, Alexandra Freeman, MD22023
516
n/a
-
v
Utkucan Acar, Gloria Sheng, Terrie Ahn, Lisa Kohn, Maria Garcia Lloret, Manish Butte
2022
82
n/a