Date: 26 November 2013
Secondary metabolites, 3D structure: Trivial name – aspochalasin C
Copyright: n/a
Notes:
Species: A. microcysticusSystematic name: 1H-Cycloundec[d]isoindole-1,11,12,15(2H)-tetrone, 3,3a,4,6a,9,10,13,14-octahydro-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,15aS)-Molecular formulae: C24H33NO4Molecular weight: 399Chemical abstracts number: 72363-48-5Selected references: Keller-Schierlein, Walter; Kupfer, Ernst (Org. Chem. Lab., ETH, Zurich CH-8092, Switz.). Helv. Chim. Acta, 62(5), 1501-24 (German) 1979.
Images library
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BAL specimen showing hyaline, septate hyphae consistent with Aspergillus, stained with Blankophor
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Mucous plug examined by light microscopy with KOH, showing a network of hyaline branching hyphae typical of Aspergillus, from a patient with ABPA.
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Corneal scraping stained with lactophenol cotton blue showing beaded septate hyphae not typical of either Fusarium spp or Aspergillus spp, being more consistent with a dematiceous (ie brown coloured) fungus
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Corneal scrape with lactophenol cotton blue shows separate hyphae with Fusarium spp or Aspergillus spp.
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A filamentous fungus in the CSF of a patient with meningitis that grew Candida albicans in culture subsequently.
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Transmission electron micrograph of a C. neoformans cell seen in CSF in an AIDS patients with remarkably little capsule present. These cells may be mistaken for lymphocytes.
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India ink preparation of CSF showing multiple yeasts with large capsules, and narrow buds to smaller daughter cells, typical of C. neoformans
