versicolorin A

ID 2: 588

Toxin: y

Systematic name: Anthra(2,3-b)furo(3,2-d)furan-5,10-dione, 3a,12a-dihydro-4,6,8-trihydroxy-, Z-(-)- Z-(-)-4,6,8-Trihydroxy-3a,12a-dihydroanthra(2,3-b)furo(3,2-d)furan-5,10-dione 4,6,8-Trihydroxy-3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione Anthra[2,3-b]furo[3

Molecular formulae: 

C18H10O7

Molecular weight: 338.268

Chemical abstract number: 6807-96-1

Chemical type: Difuroanthraquinone

Literature reference:

  • Mori H, Kitamura J, Sugie S, Kawai K, Hamasaki T. Genotoxicity of fungal metabolites related to aflatoxin B1 biosynthesis. Mutat Res. 1985 Jul;143(3):121-5.
    Anderson MS, Dutton MF. Biosynthesis of versicolorin A. Appl Environ Microbiol. 1980 Oct;40(4):706-9.

References URL: 

Aspergillus Species known to produce this metabolite:

Toxicity:

Little or no recorded toxicity in vertebrates but important as a representative of a group of metabolites which are precursors of the aflatoxins and sterigmatocystins.
mouse LD50 intravenous 20mg/kg (20mg/kg) “CRC Handbook of Antibiotic Compounds,” Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 3, Pg. 189, 1980.
Bennett JW, Christensen SB. New perspectives on aflatoxin biosynthesis.
Adv Appl Microbiol. 1983;29:53-92.

Structure image:  

VersicolorinAweb

Date uploaded: 2005-12-16 00:00:00


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