sphingofungin B

ID 2: 560

Toxin: n

Systematic name: 6-Eicosenoic acid, 2-amino-3,4,5,14-tetrahydroxy- (2S,5S,3R,4R,14R)-2-Amino-3,4,5,14-tetrahydroxyicos-6-enoic acid

Molecular formulae: 


Molecular weight: 389.527

Chemical abstract number: 121025-45-4


Literature reference:

  • VanMiddlesworth F, Giacobbe RA, Lopez M, Garrity G, Bland JA, Bartizal K, Fromtling RA, Polishook J, Zweerink M, Edison AM, et al. J Antibiot (Tokyo). 1992 Jun;45(6):861-7. Sphingofungins A, B, C, and D; a new family of antifungal agents. I. Fermentation, isolation, and biological activity.
    Zweerink MM, Edison AM, Wells GB, Pinto W, Lester RL. Characterization of a novel, potent, and specific inhibitor of serine palmitoyltransferase.
    J Biol Chem. 1992 Dec 15;267(35):25032-8.

References URL: 

Aspergillus Species known to produce this metabolite:

Structure image:  


Date uploaded: 2008-07-14 10:22:26

Mycotoxin & Metabolites

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