Deoxypodophyllotoxin

ID 2: 636

Toxin: n

Trivial name:

Furo[3′,​4′:6,​7]​naphtho[2,​3-​d]​-​1,​3-​dioxol-​6(5aH)​-​one, 5,​8,​8a,​9-​tetrahydro-​5-​(3,​4,​5-​trimethoxyphenyl)​-​, [5R-​(5α,​5aβ,​8aα)​]​-; Podophyllotoxin, deoxy- (6CI,​7CI,​8CI); (-​)​-​Anthricin; (-​)​-​Deoxypodophyllotoxin; (-​)​-​Desoxypodophyllotoxi​n; 4-​Deoxypodophyllotoxin; AS 2-​3; Anthricin; Deoxypodophyllotoxin; Desoxypodophyllotoxi​n; Silicicolin

Systematic name:

Furo(3′,4′:6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha))-

Molecular formulae: 

C22H22O7

Molecular weight: 398.41

Chemical abstract number: 19186-35-7

Literature reference:

  • Microbial transformation of an antitumor substance, deoxypodophyllotoxin. Part II. Conversion of deoxypodophyllotoxin to podophyllotoxin-​related compounds by microbes. Kondo, Kazuhiko; Ogura, Masaru; Midorikawa, Yuichiro; Kozawa, Mitsugi; Tsujibo, Hiroshi; Baba, Kimiye; Inamori, Yoshihiko. Agricultural and Biological Chemistry (1989), 53(3), 777-82.
    Aspergillus fumigatus Fresenius, an endophytic fungus from Juniperus communis L. Horstmann as a novel source of the anticancer pro-​drug deoxypodophyllotoxin. Kusari, S.; Lamshoeft, M.; Spiteller, M. Journal of Applied Microbiology (2009), 107(3), 1019-1030.

References URL: 

Aspergillus Species known to produce this metabolite:

Toxicity:

Anticancer drug

Structure image:  

Date uploaded: 2009-06-25 22:45:30


Mycotoxin & Metabolites

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