Austalide E

Systematic name:

5H-​3,​5a-​Epoxy-​12H-​furo[3,​4-​i]​oxepino[4,​3-​a]​xanthen-​12-​one, 6-​(acetyloxy)​-​1,​2,​3,​6,​7,​7a,​10,​14,​14a,​14b-​decahydro-​1-​hydroxy-​3,​13-​dimethoxy-​5,​5,​7a,​9,​14b-​pentamethyl-​, (1R,​3S,​5aR,​6R,​7aS,​14aR,​14bS)​-

Molecular formulae: 


Molecular weight: 532.58

Chemical abstract number: 81543-05-7

Literature reference:

  • Structures of the austalides A-​E, five novel toxic metabolites from Aspergillus ustus. Horak, R. Marthinus; Steyn, Pieter S.; Van Rooyen, Petrus H.; Vleggaar, Robert; Rabie, Christiaan J. Journal of the Chemical Society, Chemical Communications (1981), (24), 1265-7.
    Metabolites of Aspergillus ustus. Part 1. Application of the heteronuclear selective population inversion (SPI) NMR technique to the structure elucidation of the austalides A-​F, novel ortho ester meroterpenoids. Horak, R. Marthinus; Steyn, Pieter S.; Vleggaar, Robert; Rabie, Christiaan J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1985), (2), 345-56.
    Promoter activity enhancers containing austalide analogs, their production with Aspergillus, and method for enhancing promoter activity. Tanaka, Isshin; Shinya, Kazuo; Takagi, Motoki. PCT Int. Appl. (2012), WO 2012147905 A1 20121101

References URL: 

Aspergillus Species known to produce this metabolite:

Structure image:  

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