Aspochalasin I

Toxin: y

Systematic name:

2H-​Oxacyclododecino[2,​3-​d]​isoindole-​2,​16(5H)​-​dione, 6,​7,​8,​10a,​13,​13a,​14,​15-​octahydro-​5,​6-​dihydroxy-​9,​12,​13-​trimethyl-​14-​(2-​methylpropyl)​-​, (3E,​5R,​6S,​9E,​10aS,​13S,​13aS,​14S,​16aR)​-

Molecular formulae: 

C₂₄H₃₅NO₅

 

Molecular weight: 417.5

Chemical abstract number: 670225-69-1

Literature reference:

• Aspochalasins I, J, and K: three new cytotoxic cytochalasans of Aspergillus flavipes from the rhizosphere of Ericameria laricifolia of the Sonoran desert. Zhou, Guang-Xiong; Wijeratne, E. M. Kithsiri; Bigelow, Donna; Pierson, Leland S., III; VanEtten, Hans D.; Gunatilaka, A. A. Leslie. Journal of Natural Products (2004), 67(3), 328-332.

References URL: 

• http://pubs.acs.org/doi/abs/10.1021/np030353m?source=chemport&cookieSet=1&cookieSet=1&cookieSet=1&cookieSet=1

Aspergillus Species known to produce this metabolite:

• /species/flavipes

Toxicity:

Melanogenesis inhibitor

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Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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