α-sarcin

ID 2: 549

Toxin: n

Systematic name: 2-Amino-1-methyl-9H-purine-6-thione 9H-Purine-6-thione, 2-amino-1-methyl- Purine-6(1H)-thione, 2-amino-1-methyl- 6H-Purine-6-thione, 2-amino-1,7-dihydro-1-methyl- (9CI)

Molecular formulae: 

C6H7N5S

Molecular weight: 181.219

Chemical abstract number: 1320-87-2

Literature reference:

  • Lin A, Huang KC, Hwu L, Tzean SS. Toxicon. 1995 Jan;33(1):105-10. Production of type II ribotoxins by Aspergillus species and related fungi in Taiwan.
    OLSON BH, GOERNER GL. ALPHA SARCIN, A NEW ANTITUMOR AGENT. I. ISOLATION, PURIFICATION, CHEMICAL COMPOSITION, AND THE IDENTITY OF A NEW AMINO ACID. Appl Microbiol. 1965 May;13:314-21.
    Kao R, Davies J. Fungal ribotoxins: a family of naturally engineered targeted toxins? Biochem Cell Biol. 1995 Nov-Dec;73(11-12):1151-9. Review.



References URL: 

Aspergillus Species known to produce this metabolite:

Toxicity:

mouse LDLo 50mg/kg (50mg/kg) Journal of Medicinal and Pharmaceutical Chemistry. Vol. 5, Pg. 996, 1962.

Structure image:  

alpha-sarcinweb

Date uploaded: 2008-07-07 13:14:58


Mycotoxin & Metabolites

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