Activity of pradimicin BMS-181184 against Aspergillus spp.

The pradimicins are a new class of antifungal agents with activity against the majority of human fungal pathogens. In this study, the in vitro activity of pradimicin BMS-181184 was investigated against a range of the most common species of Aspergillus. The results were compared with itraconazole and amphotericin B. BMS-181184 was found to be active against most Aspergillus spp., but at higher concentrations than itraconazole and amphotericin B.

Antifungal name: 

Date of article/Start date of trial: 

Wednesday, August 25, 1999

Trial phase: 

Phase 1
New antifungal drugs