|
Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei |
Tacrolimus |
|
19 Mar 2003 |
|
Combination of caspofungin with inhibitors of the calcineurin pathway attenuates growth in vitro in Aspergillus species |
Tacrolimus |
|
20 Feb 2003 |
|
The immunosuppressant FK506 (tacrolimus) and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein |
Tacrolimus |
|
11 Jan 1997 |
|
Inhibitors of fungal GWT1 and MCD4 discovered through Candida albicans fitness test |
L884 |
|
8 Sep 2014 |
|
Inhibitors of fungal GWT1 and MCD4 discovered through Candida albicans fitness test |
L743 |
|
8 Sep 2014 |
|
Inhibitors of fungal GWT1 and MCD4 discovered through Candida albicans fitness test |
L365 |
|
11 Oct 2017 |
|
Drugs in Clinical Development for Fungal Infections (includes MAT023, encochleated amphotericin B)) |
Encochleated AmB (MAT023) |
|
24 Aug 2017 |
|
Antitumor/Antifungal Celecoxib Derivative AR-12 is a Non-Nucleoside Inhibitor of the ANL-Family Adenylating Enzyme Acetyl CoA Synthetase |
AR-12 |
Phase 1 |
8 Apr 2016 |
|
The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis |
AR-12 |
|
17 Nov 2016 |
|
Synthesis and antifungal activity of ASP9726, a novel echinocandin with potent Aspergillus hyphal growth inhibition |
ASP9726 |
|
13 Feb 2014 |
