Canescin

ID 2: 377

Toxin: n

Trivial name:

1-​Demethoxyreserpine; 11-​Desmethoxyreserpine; Canescin; Canescine; Canescine (Rauwolfia); Deserpic acid, methyl ester, 3,​4,​5-​trimethoxybenzoate; Deserpidin; Harmonyl; NSC 72138; Raunormin; Raunormine; Recanescin; Recanescine; Reserpidine

Systematic name:

Yohimban-​16-​carboxylic acid, 17-​methoxy-​18-​[(3,​4,​5-​trimethoxybenzoyl)​oxy]​-​, methyl ester, (3β,​16β,​17α,​18β,​20α)​-

Molecular formulae: 

C₃₂H₃₈N₂O₈

 

Molecular weight: 578.7

Chemical abstract number: 131-01-1

Literature reference:

• A deuterium and carbon-​13 NMR study of the biosynthesis of the polyketide isocoumarin residue of canescin in Aspergillus malignus from acetate-​1,​2-​13C2 and -​1-​13C-​2-​d3, methionine-​Me-​13C,​d3, 6,​8-​dihydroxy-​3,​7-​dimethylisocoumarin, and 6,​8-​dihydroxy-​7-​formyl-​3-​methylisocoumarin. Lewis, Christopher N.; Staunton, James; Sunter, David C. Journal of the Chemical Society, Chemical Communications (1986), (1), 58-60.
  Standardized high-​performance liquid chromatography of 182 mycotoxins and other fungal metabolites based on alkylphenone retention indexes and UV-​VIS spectra (diode array detection). Frisvad, Jens; Thrane, Ulf. Journal of Chromatography (1987), 404(1), 195-214.

References URL: 

• http://pubchem.ncbi.nlm.nih.gov/compound/8550
• http://pubs.rsc.org/en/Content/ArticleLanding/1986/C3/c39860000058#!divAbstract
• http://www.sciencedirect.com/science/article/pii/S0021967301868503

Aspergillus Species known to produce this metabolite:

• /species/a-malignus

Date uploaded: 2008-07-07 15:48:31

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Mycotoxin & Metabolites

Mycotoxin & Metabolite database

Aspergillus species produce a large number of secondary metabolites, sometimes referred to as extrolites. We attempt to list them all here and we also collect published papers.

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