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Title Legend Grouping
Libero Ajello, 1916 - 2004 Libero Ajello, 1916 - 2004
Charles Thom, 1872 - 1956 Charles Thom, 1872 - 1956
Pier Antonio Micheli, 1679-1737 Pier Antonio Micheli, 1679-1737
David Gruby, 1810 - 1898 David Gruby, 1810 - 1898
John Hughes Bennett, 1812-1875 John Hughes Bennett, 1812-1875, John Hughes Bennett, 1812-1875
John Hughes Bennett, 1812-1875, John Hughes Bennett, 1812-1875 John Hughes Bennett, 1812-1875

Bennett's portrait at the Royal College of Physicians of Edinburgh

In his 1842 paper Bennett gave the earliest description of pulmonary aspergillosis. Bennett was one of the first to recognise the importance of the microscope in the clinical investigation of disease and his use of the instrument was central to identifying the presence of a fungus in the sputum and, post mortem, lungs of the patient with aspergillosis.

biography on Wikipedia

An obituary from the British Medical Journal of 1875

John R. S. Fincham, 1926–2005 John R. S. Fincham, 1926–2005
Edouard Drouhet, 1919 - 2000 Edouard Drouhet, 1919 - 2000
Friedrich Staib, 1925 - 2011 Friedrich Staib, 1925 - 2011
Gabriel Segretain, 1913 - 2008 Gabriel Segretain, 1913 - 2008
MARGARET B. CHURCH, 1889-1976 MARGARET B. CHURCH, 1889-1976
Piero Martino, 1946–2007 Piero Martino, 1946–2007
John Pateman, 1926 - 2011 John Pateman, 1926 - 2011
Dorothy Fennell, 1926 - 1977 Dorothy Fennell, 1926 - 1977
Kenneth Raper, 1908-1987 Kenneth Raper, 1908-1987
Pt SD Congestive heart failure with itraconazole Pt SD congestive heart failure 5 images PtSD1 CT scan Jan 14, PtSD2  CT scan2 Jan 14, PtSD3 CT scan3 Jan 14, PtSD2 Congestive heart failure with Itraconazole Chest x ray Jan 14, PtSD2 Congestive heart failure with Itraconazole Chest x ray May14
PtSD1 CT scan Jan 14, PtSD2  CT scan2 Jan 14, PtSD3 CT scan3 Jan 14, PtSD2 Congestive heart failure with Itraconazole Chest x ray Jan 14, PtSD2 Congestive heart failure with Itraconazole Chest x ray May14 Pt SD Congestive heart failure with itraconazole Pt SD congestive heart failure 5 images

This 63 year old woman with a lung nodule, probably caused by Aspergillus, was treated with itraconazole 300mg daily. After 3 weeks, she noticed dizziness and her blood pressure was reduced at 100/60.  A week later, she was complaining of headaches, feeling unwell and fluctuating blood pressure. Her BP was 133/62 and pulse 90/min and regular. Her thyroid replacement therapy was excessive and so reduced, as was her itraconazole dose, although subsequent itraconazole levels were in the therapeutic range. Six days later she was admitted to hospital very breathless with bilateral pleural effusions. Itraconazole was stopped.

Her CXR shows bilateral effusions, probable cardiac enlargement and some upper lobe vessel fullness in the lungs. The CT scan confirms bilateral flexural effusions, with associated consolidated lung and fluid in the fissure on the right. The heart is enlarged and right ventricle dilated. In May, all had resolved and she is left with a nodule in the left lower lobe.

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