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Echinocandin B 3d
EchinocandinB-kern 3d
Mucous containing Charcot-Leyden crystals Mucous containing Charcot-Leyden crystals, stained with H read more...
Mucous containing Charcot-Leyden crystals Mucous containing Charcot-Leyden crystals, stained with H read more... Mucoid impaction due to ABPA- Pt DL.A 57 year old woman presented with breathlessness. She had a history of mild asthma for which she occasionally took salbutamol inhaler puffs. The patient underwent a pneumonectomy because of the severity of her disease process, and uncertainty about the diagnosis, prior to serology results being obtained.Serology showed an IgE of 2600, with a strongly positive Aspergillus RAST test and weakly positive Aspergillus precipitins. Material removed at bronchoscopy showed eosinophilia. These features confirm a diagnosis of allergic bronchopulmonary aspergillosis (ABPA).
Saccular bronchiectasis A Bronchogram showing saccular bronchiectasis
Saccular bronchiectasis A Bronchogram showing saccular bronchiectasis <p style="font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 1.5; color: rgb(24, 0, 82); background-color: rgb(254, 254, 237);">Bronchography&nbsp;<strong>(A &amp; B</strong>)is an old technique for visualising the bronchial tree, by introducing radio-opaque dye into the airways and then taking a chest Xray. It was the first means used to diagnose bronchiectasis, seen in these examples below. An historical description of the technique from 1922 can be<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/.../pdf/tacca200047-0064.pdf" style="color: rgb(0, 0, 213);">&nbsp;seen here</a>&nbsp;</p> <p style="font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 1.5; color: rgb(24, 0, 82); background-color: rgb(254, 254, 237);">Nowadays CT scanning of the chest is used for this purpose with 3D reconstruction in some cases.&nbsp;<br /> <br /> White cell scan (<strong>C</strong>) This pair of white cell scans from different people show almost no white cells in the lungs on the left, as in a healthy person (the spleen is the ‘hottest area). The scan on the right shows grossly increased update, especially in the left lung (seen on the right). This is the typical feature of severe bronchiectasis with large amounts of neutrophils and other phagocytes present. &nbsp;</p> <p style="font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 1.5; color: rgb(24, 0, 82); background-color: rgb(254, 254, 237);">Sinusitis Plain X-ray&nbsp;<strong>(D</strong>) of the face showing the maxillary sinuses. The right maxillary sinus is complete fluid filled and the left side (seen on the right) has a fluid level. These features may be seen with severe acute bacterial sinusitis, but also other causes of sinusitis, including allergic rhinosinusitis. &nbsp;</p>
Bronchiectasis B Bronchogram showing bronchiectasis
Bronchiectasis B Bronchogram showing bronchiectasis <p style="font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 1.5; color: rgb(24, 0, 82); background-color: rgb(254, 254, 237);">Bronchography&nbsp;<strong>(A &amp; B</strong>)is an old technique for visualising the bronchial tree, by introducing radio-opaque dye into the airways and then taking a chest Xray. It was the first means used to diagnose bronchiectasis, seen in these examples below. An historical description of the technique from 1922 can be<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/.../pdf/tacca200047-0064.pdf" style="color: rgb(0, 0, 213);">&nbsp;seen here</a>&nbsp;</p> <p style="font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 1.5; color: rgb(24, 0, 82); background-color: rgb(254, 254, 237);">Nowadays CT scanning of the chest is used for this purpose with 3D reconstruction in some cases.&nbsp;<br /> <br /> White cell scan (<strong>C</strong>) This pair of white cell scans from different people show almost no white cells in the lungs on the left, as in a healthy person (the spleen is the ‘hottest area). The scan on the right shows grossly increased update, especially in the left lung (seen on the right). This is the typical feature of severe bronchiectasis with large amounts of neutrophils and other phagocytes present. &nbsp;</p> <p style="font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 12px; line-height: 1.5; color: rgb(24, 0, 82); background-color: rgb(254, 254, 237);">Sinusitis Plain X-ray&nbsp;<strong>(D</strong>) of the face showing the maxillary sinuses. The right maxillary sinus is complete fluid filled and the left side (seen on the right) has a fluid level. These features may be seen with severe acute bacterial sinusitis, but also other causes of sinusitis, including allergic rhinosinusitis. &nbsp;</p>
Pt HK Chronic cavitary pulmonary aspergillosis responding to posaconazole Born 75 years ago, Pt HK had 3 episodes of tuberculosis as a child and teenager, being treated with PAS and streptomycin.  He suffered a ‘bad chest’ all his life and retired aged 54.  Presenting with worsening and more frequent chest read more... Chest X-ray 13/11/09
Chest X-ray 13/11/09 Pt HK Chronic cavitary pulmonary aspergillosis responding to posaconazole Born 75 years ago, Pt HK had 3 episodes of tuberculosis as a child and teenager, being treated with PAS and streptomycin.  He suffered a ‘bad chest’ all his life and retired aged 54.  Presenting with worsening and more frequent chest read more...
Bronchiectasis C Bronchiectasis white cell scan (right) - left shows a normal scan for comparison
Bronchiectasis C Bronchiectasis white cell scan (right) - left shows a normal scan for comparison

White cell scan (C) This pair of white cell scans from different people show almost no white cells in the lungs on the left, as in a healthy person (the spleen is the ‘hottest area). The scan on the right shows grossly increased update, especially in the left lung (seen on the right). This is the typical feature of severe bronchiectasis with large amounts of neutrophils and other phagocytes present.

Pt NW Mucoid impaction, localised bronchiectasis and surgery (upper lobectomy) in a patient with ABPA Macroscopic view medial aspect of left upper lobe of lung showing segmental collapse and congestion of lower segments, with mucus extruding from incised bronchi. Image A. Macroscopic view medial aspect of left upper lobe of lung showing segmental collapse and congestion of lower segments, with mucus extruding from incised bronchi., Image B. Macroscopic view of sliced left upper lobe of lung showing obstruction of lower segmental bronchi by impacted mucus., Image C. Low power microscopic view, haematoxylin and eosin staining, of obstructed bronchus with typical ‘laminated’ appearance – alternating layers of mucus and inflammatory cells., Image D. Higher power microscopic view, haematoxylin and eosin staining, showing goblet cell hyperplasia of bronchial epithelium and inflammatory infiltrate including numerous eosinophils, Image E. High power microscopic view, Grocott silver staining, showing scanty fungal hyphae in mucus.
Image A. Macroscopic view medial aspect of left upper lobe of lung showing segmental collapse and congestion of lower segments, with mucus extruding from incised bronchi., Image B. Macroscopic view of sliced left upper lobe of lung showing obstruction of lower segmental bronchi by impacted mucus., Image C. Low power microscopic view, haematoxylin and eosin staining, of obstructed bronchus with typical ‘laminated’ appearance – alternating layers of mucus and inflammatory cells., Image D. Higher power microscopic view, haematoxylin and eosin staining, showing goblet cell hyperplasia of bronchial epithelium and inflammatory infiltrate including numerous eosinophils, Image E. High power microscopic view, Grocott silver staining, showing scanty fungal hyphae in mucus. Pt NW Mucoid impaction, localised bronchiectasis and surgery (upper lobectomy) in a patient with ABPA Macroscopic view medial aspect of left upper lobe of lung showing segmental collapse and congestion of lower segments, with mucus extruding from incised bronchi.

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