High power view of elastin fibres in an arterial wall being forced apart by Aspergillus hyphae. As Aspergillus is angiotropic and produces an elastase, it was uncertain how it traversed vessel walls. It appears to do so without any dissolution of elastin fibres.
Â© Denning DW, Ward PN, Fenelon LE, Benbow EW. Lack of vessel wall elastolysis in human invasive pulmonary aspergillosis. Infect Immun 1992; 60: 5153-5156