International Course on Antibiotics and Resistance

Conference abbreviation: ICARe

Title:

ASM microbe 2016

Date uploaded: 13 August 2018

Conference Year: 2018

Location:

Les Pensières, Annecy, France

Further information:

ICARe is designed for early career scientists – assistant professors, new industry scientists, MDs, and postdoctoral research associates – as well as members from developing areas contending with the practical challenge of managing the antibiotic resistance problem with limited resources. Attendance will be limited to 40 students and will reflect the global nature of the problem.aza

The course will be administered over 8 days and will consist of formal instruction, review of the literature, small group problem solving including hands-on use of relevant computational tools, innovation-driven brainstorming sessions, and network building.

THE THEMES OF THE CONFERENCES

  • Current infectious disease management and antibiotic use
  • Modes of action and mechanisms of resistance of existing classes : Cell wall, Ribosome, Nucleic acid synthesis / replication / transcription, Efflux
  • Origin, mutations, and identifications of antibiotic resistance mechanisms
  • Antibiotic discovery
  • Antibiotic chemical matter : Natural products, synthetics
  • Antibiotic development and approval
  • New topics in antibiotic discovery
  • Strategies for more focused applications of antibiotics
  • New technologies for determination of susceptibility and detection of resistance
  • New antiinfective strategies

THE THEMES OF THE PRACTICAL WORK

  • Choosing the DNA sequencing technology
  • Data bases for antibiotic resistance and virulence
  • Detection and identification of resistance genes
  • Mobile genetic elements
  • TnSeq, RNASeq
  • Functional genomics
  • Phylogeny

The objective of the course is to train the next generation of scientists implicated in the study of bacterial resistance to antibiotics and the finding of new drugs

The faculty is composed of 40 internationally recognized scientists and physicians who have made important contributions to antibiotic development, and infectious diseases and resistance management. Faculty will be in residence for a minimum of two days and  accessible for informal interactions. Graduates will emerge with a state-of-the-art understanding of existing antibiotics: modes of action, pharmacology, toxicology, mechanisms of resistance, impact of antibiotics on human and other ecologies, current approaches for mining chemical space for antimicrobial activity, the process of advancing hits to leads, the application of next generation nucleic acid-based technologies for antibiotic discovery and resistance detection, and perhaps, most importantly, training and experience in thinking creatively and innovatively about solutions to the problem. The course aims to build an international cadre of collaborative, well networked, and highly trained specialists.

Start and End Date: 6 October 2018, 14 October 2018


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