xanthomegnin

Toxin: 

y

Systematic name: 

(8,8'-Bi-1H-naphtho(1,2-c)pyran)-1,1',7,7',10,10'-hexone, 3,3',4,4'-tetrahydro-6,6'-dihydroxy-9,9'-dimethoxy-3,3'-dimethyl-, (3R,3'R)- (8CI) (8,8'-BI-1H-NAPHTHO(2,3-c)PYRAN)-1,1',6,6',9,9'-HEXONE, 3,3',4,4'-TETRAHYDRO-10, (8,8'-Bi-1H-naphtho(2,3-c)pyran

Molecular formulae: 

C30H22O12

Molecular weight: 

574.488

Chem abstract number: 

1685-91-2

Literature reference: 

Durley RC, MacMillan J, Simpson TJ, Glen AT, Turner WB. Fungal products. Part XIII. Xanthomegnin, viomellin, rubrosulphin, and viopurpurin, pigments from Aspergillus sulphureus and Aspergillus melleus. J Chem Soc [Perkin 1]. 1975;(2):163-9.
Stack ME, Mislivec PB. Production of xanthomegnin and viomellein by isolates of Aspergillus ochraceus, Penicillium cyclopium, and Penicillium viridicatum. Appl Environ Microbiol. 1978 Oct;36(4):552-4.

Chemical type: 

Dihydroisocoumarin

Toxicity: 

Doses of 448 mg/kg body-weight in mice caused symptoms of liver damage including jaundice, necrotising cholangitis and other histological alterations. Robbers JE, Hong S, Tuite J, Carlton WW. Production of xanthomegnin and viomellein by species of Aspergillus correlated with mycotoxicosis produced in mice. Appl Environ Microbiol. 1978 Dec;36(6):819-23.

History: 

Structure image: 

Aspergillus Species known to produce this metabolite: 

Date uploaded: 

2008-07-14 11:13:57