Unusual and rare fungal pathogens - A report

Reshmi Gopalakrishnan*.G.S.Vijay Kumar and Sowmya G.S

Author address: 

JSS Medical College, Mysore-570 015

Abstract: 

Modem health care facilities have improved the living conditions of immunosuppressed persons, but this has resulted in newer invasive fungal diseases. Apophysomyces is a thermotolerant fungus often causing fatal infection. Ochroconis, an ubiquitous black mold, is being increasingly isolated from organ transplant recipients. Stephanoascus is a well known opportunistic pathogen but fatality is less common. Intuition to rule out opportunistic fungi in suspected mycotic illness helps in saving the infected person. Three cases of unusual fungal infections were diagnosed during one year period. A case of fatal necrotizing anterior abdominal wall fasciitis due to Apophysomyces variabilis, a case of subcutaneous ulcerative chromoblastomycosis caused by Ochroconis constricta and a case of oral thrush caused by Stephanoascus ciferrii were reported. Necrosed tissue bit from a case of anterior abdominal wall fasciitis, tissue bit/discharge from the ulcerative lesion on leg and oral swab from a case of white patch in oral cavity were examined employing different mycological diagnostic methods. Macroscopic and microscopic evidences helped to identify three rare fungal pathogens. Gene Sequencing and phylogenetic analysis identified Apophysomyces variabilis. Phylogenetic analysis identified O. constrica and S. ciferrii respectively. Knowledge of newer pathogens and proper identification of the unusual pathogens helps initiation of suitable antifiuigal treatment. Active diagnostic bench work and a wide angled thinking of possible fungal disease is very vital. Keywords: Apophysomyces variabilis, Ochroconis constrica, Stephanoascus ciferrii. 9830;Corresponding author E-mail:[email protected]
2014

abstract No: 

OP-006

Full conference title: 

Society for Indian Human and Animal Mycologists 2014
    • SIHAM