Top 10 papers in the field of Fungal Basic research

N. Osherov

Author address: 

Tel-Aviv University, Tel-Aviv, Israel

Abstract: 

The lecture will outline exciting developments in our understanding of the basic biology of pathogenic fungi (discovery of a sexual cycle in Aspergillus fumigatus; Nature 457:471-5, 2008, Candida albicans biofilm formation; PLOS Biol. 7:e1000133, 2009), novel genes affecting virulence in C. albicans (PNAS 106:599-604, 2009) and Cryptococcus neoformans (Cell 135:174-88, 2008), host recognition of fungal infections (dectin1 receptor null mice: J. Immunol.182:4938-46, 2009; neutrophil NETS: Cell Microbiol. 8:668-76, 2006) and novel therapeutic strategies emanating from basic research (Hsp90 inhibitors: PNAS 106:2818-23, 2009; Deducing the mode of action of new antifungal compounds :PLOS Path. 3:e92, 2007). I will attempt to describe why basic fungal research has advanced so rapidly in the last few years and what can be expected in the near future.
2009

abstract No: 

W13.3

Full conference title: 

4th Trends in Medical Mycology
    • TIMM 4th (2012)