Temperature sensitive swo (swollen) mutants of Aspergillus nidulans have been isolated. They represent eight genes that may be involved in polarity establishment, polarity maintenance and hyphal morphogenesis. One of these mutants, swoA, grows isotropically at restrictive temperature, and is unable to produce a germ tube. When shifted from restrictive to permissive temperature, multiple normal sized germ tubes emerge. Conversely, a shift from permissive to restrictive temperature halts elongation and isotropic swelling begins. Currently, further characterization and cloning experiments of swoA are being conducted.
Fungal Genet. Newsl. 46 (Supl):
Full conference title:
Fungal Genetics Conference 20th
- Fungal Genetics Conference 20th (1999)