Susceptibility profile of deep-seated yeasts isolates from a university hospital in the northern region of Portugal

I. Faria-Ramos*, J. Santos-Antunes, S. Costa-de-Oliveira, A.G. Rodrigues, C. Pina-Vaz

Author address: 

(Porto, PT)


Objectives: An observational study was conducted at the biggest hospital in Portugal, aiming to evaluate the susceptibility profile of yeasts isolated from invasive fungal infections and relevant epidemiological data. Methods: Between September 2010 and 2011, all yeasts isolated from invasive fungal infections admitted at the university hospital S. João, in Porto, were collected. All strains were identified using Vitek2 system and the antifungal susceptibility profile was determined according to CLSI M27-A3 protocol regarding eight antifungals. Clinical and demographic data were registered. Mortality attributed to fungal infections was calculated. Chi-square test and multivariable logistic regression were used to analyze data. Results: The incidence of invasive infections was 3.2 per 1000 admissions. One hundred and forty six isolates were collected, from blood (61.5%), peritoneal liquid (29.5%), cerebrospinal fluid (6.4%) and pleural effusion (2.6%) cultures. Fifty-two percent corresponded to Candida albicans, followed by C. glabrata (15.2%), C. parapsilosis

abstract No: 


Full conference title: 

22nd European Congress of Clinical Microbiology and Infectious Diseases
    • ECCMID 22nd (2012)