Specific IgE to indoor molds in patients with respiratory allergies9734;

D. Galantea, P.A. Tassinaria, A. Conesaa, E. Trejob, N.E. Biancoa

Author address: 

a Institute of Immunology, Universidad Central de Venezuela, Caracas, Venezuela b Institute of Experimental Medicine, Universidad Central de Venezuela, Caracas, Venezuela


Rationale To evaluate the importance of sensitivity to molds in patients living in Caracas with persistent allergic rhinitis (PAR) and/or bronquial asthma (BA). Methods We evaluated 139 patients from the outpatient clinic of the Institute of Immunology, 6 to 55 years old, with PAR and/or BA, and positive questionnaire for molds exposures in their houses. A panel of inhalants and molds skin tests (Prick) were performed to all patients. Total serum IgE was measured and specific IgE to indoor molds was evaluated by RAST, basophil histamine release test (BHRT) and basophil activation test (BAT) in 10 patients with positive mold skin test. Results Thirty two patients were positive to at least one mold antigen (Prick), being the most frequents: Candida, Aspergillus, Rhizopus, Neurospora and Alternaria. The presence of damping was the most common inciting factor found in the questionnaire (p

abstract No: 

Page S144

Full conference title: 

2004 American Academy of Allergy, Asthma, and Immunology Annual Meeting
    • AAAAI 2004 (60th)