Serum ige antibodies against hazelnut and aspergillus in hazelnut processing workers

Naciye Karatas, Ege Gulec Balbay, Peri Arbak, Ozlem Yavuz, Songul Uygun, Ali Nihat Annakkaya, Oner Balbay

Author address: 

1Chest Diseases, Antakya State Hospital, Antakya, Turkey 2Chest Diseases, Ataturk State Hospital, Duzce, Turkey 3Chest Diseases, Duzce University Faculty of Medicine, Duzce, Turkey 4Biochemistry, Duzce University Faculty of Medicine, Duzce, Turkey


To evaluate the association between the hazelnut sensitisation and workplace related respiratory complaints 82 hazelnut processing workers were undergone a questionnaire, pulmonary function testing and measurement of serum IgE antibodies against hazelnut and aspergillus. Thirteen (15.9 %) workers had specific IgE antibodies against hazelnut whereas 3 workers (3.7%) produced antibodies against aspergillus and 1 (1.2%) had antibodies against both hazelnut and aspergillus. Breathlessness was higher in seropositive workers than seronegative workers (7.1% vs 4.4%). Sixteen seronegative workers (23.5%) and 4 seropositive workers (28.6%) were smokers. Mean FVC (2680.8 vs 2467.5 ml), FEV1 (2953.8 vs 2722.5 ml), FEV1/FVC ratio (91.1% vs 91.0%) and MMF (3304.0 vs 3206.6 ml/sec) in seronegative hazelnut workers were slightly higher than seropositive workers. Mean working duration of seropositive workers was 24.0±17.3 years whereas it was 27.8±21.3 years in seronegative workers. In linear regression analysis, allergy history, smoking, hazelnut allergy and working duration were not found to have an independent effect on breathlessness. In conclusion; only breathlessness was more common in seropositive hazelnut workers. Being sensitised to hazelnut was not found to be associated with work related respiratory symptoms in this case.

abstract No: 


Full conference title: 

20th European Respiratory Society conference
    • ERS 20th (2010)