To evaluate the association between the hazelnut sensitisation and workplace related respiratory complaints 82 hazelnut processing workers were undergone a questionnaire, pulmonary function testing and measurement of serum IgE antibodies against hazelnut and aspergillus. Thirteen (15.9 %) workers had specific IgE antibodies against hazelnut whereas 3 workers (3.7%) produced antibodies against aspergillus and 1 (1.2%) had antibodies against both hazelnut and aspergillus. Breathlessness was higher in seropositive workers than seronegative workers (7.1% vs 4.4%). Sixteen seronegative workers (23.5%) and 4 seropositive workers (28.6%) were smokers. Mean FVC (2680.8 vs 2467.5 ml), FEV1 (2953.8 vs 2722.5 ml), FEV1/FVC ratio (91.1% vs 91.0%) and MMF (3304.0 vs 3206.6 ml/sec) in seronegative hazelnut workers were slightly higher than seropositive workers. Mean working duration of seropositive workers was 24.0Â±17.3 years whereas it was 27.8Â±21.3 years in seronegative workers. In linear regression analysis, allergy history, smoking, hazelnut allergy and working duration were not found to have an independent effect on breathlessness. In conclusion; only breathlessness was more common in seropositive hazelnut workers. Being sensitised to hazelnut was not found to be associated with work related respiratory symptoms in this case.
Full conference title:
20th European Respiratory Society conference
- ERS 20th (2010)