s i. Sensitivity to Aspergillus flavus in Patients with Soybean Induced Asthma and/or Allergic Rhinitis

L. R. F. Ardusso ] , R. Codina 2, C. D. Crisci l , R. F. Lockley 2, J. Molinas ] , I. Medina ], S. Trobbiani], C. Lrpez 3, L. Ramos 3

Author address: 

IDepartment of Allergy and Immunology, Rosario School of Medicine, Rosario, ARGENTINA, 2Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, College of Medicine and James A. Haley VA Hospital, Tampa, F


RATIONALE: Aspergillusflavus (AF) contaminates soybean hulls (SH), which cause allergic rhinitis and asthma (AR-A) in Argentinian rural sub- ]ects. The purpose of this study is to investigate the association between sensitization to SH and molds. METHODS: Allergen extracts were prepared from SH and AF isolated from soybeans. Skin test (ST) with the SH, AF extracts, and common allergen vaccines, including a mixture of Aspergillus fumigatus and A. niger (Asp), were performed by the prick technique. Three groups of subjects were studied: (i) Group l (G1), included 71 atopics with AR-A with a positive ST to SH; (ii) group 2 (G2), 60 atopics with AR-A with a negative ST to SH; and (iii) group 3 (G3), control group, 18 healthy subjects with a negative ST to SH and common allergens. The study protocol was approved by University of Rosario. RESULTS: Twenty-six of 71 (36.6%) subjects from G1, 5/60 (8.3%) from G2 and 0/18 (0%) from G3 had a positive ST (histamine index > 0.5) to AF (p

abstract No: 


Full conference title: 

2003 American Academy of Allergy, Asthma, and Immunology Annual Meeting
    • AAAAI 2003 (59th)