Research Position: “In silico studies, selection and synthesis of low toxicity antifungal compounds active against plant pathogenic fungi”

it: Research Position: “In silico studies, selection and synthesis of low toxicity antifungal compounds active against plant pathogenic fungi” [Duties: The research will be aimed to: The research will be aimed to: (i) design and evaluation of potential inhibitory molecules by a docking study of their interaction with the trichodiene synthase protein; (ii) selection and sustainable synthesis of new natural and natural-like inhibitors of TRI5; (iii) evaluation of the effect of inhibitory molecules on fungal growth and on key physiological parameters in vitro; (iv) evaluation of the effect of new inhibitory molecules on the biosynthesis of type B trichothecenes; (v) evaluation of the effect of new inhibitory molecules on the severity of Fusariu Head Blight on wheat grown under glasshouse conditions; vi) evaluation of the effect of new inhibitory molecules on the coordinated expression of gene... | Minimum Requirements: Eligible candidates are required to possess one of following titles/qualifications: PhD’s (or equivalent foreign qualification) in all relevant sectors of expertise; Post-graduate (medical field) with an suitable number/quality of publications; OR; Bachelor’s degree or Master’s degree obtained within the Italian pre-reform 4-year university course system, issued by an Italian University or an equivalent foreign institution PLUS scientific professional certification of research experience, for a period of at least two (2) years; Failure to comply with the afore-mentioned provisions will result in exclusion from the competition] / Università degli Studi di Sassari; Sassari, Sardegna, Italy / deadline September 30