Relationship Of Allergen Sensitization and LUNG Function In Adults Patients With Asthma In Allergy Clinic In Monterrey, Mexico

Dr. Hilda Hernandez Sanchez, MD, Prof. Sandra N. Gonzalez-Diaz, MD, PhD, FAAAAI, Prof. Alejandra Macias-Weinmann, MD, Prof. Alfredo Arias-Cruz, MD, FAAAAI, Dr. Idalia Vanessa Yanez-Perez, MD, Dr. Lorena Rangel-Garza, MD

Author address: 

University Hospital Dr. Jose Eleuterio Gonzalez, UANL, Monterrey, Mexico

Abstract: 

Rationale

Sensitization to aeroallergens is known as a risk factor to development of asthma. The aim is assess relationship of sensitization to aeroallergens with lung function by spirometry in asthmatic adults treated in 2010-2012 in Regional Centre of Allergy and Clinical Immunology University Hospital in Monterrey, NL.

 

Methods

Observational, descriptive study, which consisted in a review of medical records of adult patients with asthma and sensitization to allergens tested. We obtained demographic, clinical data, results of skin tests with extracts of 36 aeroallergens and the results of pulmonary function. Were analyzed with statistical program SPSS20, and Fisher's exact test.

 

Results

From the review of medical records were selected 121patients, gender distribution was female, in 46.3%, the mean age was 34.3 years, and age ranges were <25 years (19%), 25-44 years (49.6%), 45-64 years (28.9%), <65 years (2.5%). The most frequent are Dermatophagoides spp (60.3%), Sorghum halepense (29.8%),Prosopis spp (28.9%), Cynodon dactylon (26.4%) and Blattella germanica (17.4%). In relation to pulmonary function tests, the mean FEV1 was 83%, + 18.4, with mean of reversibility of 12.95%, the age group with the greatest impaired in FEV1 was 45 to 64 years. The x2 test: relationship of FEV1with sensitization pollen (p=0.62), fungi (p=0.75), mites (p=0.31), cat (p=0.72).

 

Conclusions

The most common are Dermatophagoides spp; the relationship of sensitization and lung función measured by spirometry in these patients was not statistically significant, which may be due previous treatment, exposure to allergen, determinants genetic, environmental conditions, infections, irritants, age, which have an important role in lung function.

abstract No: 

883
    • AAAAI 2014 (70th)