ptAVA: acute IPA, following AML

Case number: 

17

pt_initials: 

-

Anonymised initials: 

ptAVA

Diagnosis: 

Acute IPA

Demographics: 

65/F

Underlying/comorbid conditions: 

Acute myeloid leukaemia

Summary: 

A 65 year old white woman with a history of refractory acute myeloid leukaemia (AML) that was resistant to chemotherapy developed probable pulmonary aspergillosis. She had neutropenia for 28 days pre-diagnosis, following recent chemotherapy and high-dose steroid use. Invasive aspergillosis was diagnosed from chest CT (nodules/consolidation) and consecutively positive antigen tests. She was refractory to itraconazole IV and amphotericin B (progression of disease) and was treated with caspofungin (70mg loading, then 50mg/day) for 29 days with stabilisation of her infection and further improvement was seen with oral itraconazole.

Species: 

  • Unknown

Tag: 

Clinic (country): 

National Aspergillosis Centre (Manchester, UK)

Initials (for sorting): 

1AVA

Teaser image: 

Photo cluster: