Pleural Aspergillosis

Case number: 



A 28 year old Caucasian man suffered a long, complicated course of definite pulmonary aspergillosis (aspergillus empyema). A chest CT showed multiple interconnected localized cavities in R lung with significant amount of fluid in the thorax, and a suspect focus in central R lung, the patient was taken to theatre where a right pleuro-pneumonectomy was performed. Persistent infection, despite treatrment, necessitated a "Claggit-cave" surgical procedure to mechanically clean for Aspergillus in R hemithorax. His disease was refractory to Amphotericin B and itraconazole initially and then to Abelcet (failure to improve for Amphotericin B and Abelcet, progression of disease for itraconazole). He was treated with caspofungin thereafter for 114 days with notable clinical improvement.


  • Aspergillus fumigatus