Paraherquamide

Toxin: 

n

Trivial name: 

Paraherquamide; (-​)​-​Paraherquamide; (-​)​-​Paraherquamide A; PNU 97333; Paraherquamide A; Spiro[4H,​8H-​[1,​4]​dioxepino[2,​3-​g]​indole-​8,​7'(8'H)​-​[5H,​6H-​5a,​9a]​(iminomethano)​[1H]​cyclopent[f]​indolizine]​-​9,​10'(10H)​-​dione, 2',​3',​8'a,​9'-​tetrahydro-​1'-​hydroxy-​1',​4,​4,​8',​8',​11'-​hexamethyl-​, [1'R-​(1'α,​5'aβ,​7'β,​8'aβ,​9'aβ)​]​-; VM 29919; [1'R-​(1'α,​5'aβ,​7'β,​8'aβ,​9'aβ)​]​-​2',​3',​8'a,​9'-​Tetrahydro-​1'-​hydroxy-​1',​4,​4,​8',​8',​11'-​hexamethylspiro[4H,​8H-​[1,​4]​dioxepino[2,​3-​g]​indole-​8,​7'(8'H)​-​[5H,​6H-​5a,​9a]​(iminomethano)​[1H]​cyclopent[f]​indolizine]​-​9,​10'(10H)​-​dione

Systematic name: 

Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione, 2',3',8'a,9'-tetrahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-

Molecular formulae: 

C28H35N3O5

Molecular weight: 

493.59

Chem abstract number: 

77392-58-6

Literature reference: 

On the structure of two new metabolites isolated from Penicillium paraherquei and aspergillus silvaticus. Yamazaki, M.; Fujimoto, H.; Okuyama, E.; Ohta, Y. Mycotoxins (1980), 10, 27-8. Combined molecular and biochemical approach identifies Aspergillus japonicus and Aspergillus aculeatus as two species. Parenicova, Lucie; Skouboe, Pernille; Frisvad, Jens; Samson, Robert A.; Rossen, Lone; ten Hoor-Suykerbuyk, Marjon; Visser, Jaap. Applied and Environmental Microbiology (2001), 67(2), 521-527. Detection of VM55599 and preparaherquamide from Aspergillus japonicus and Penicillium...

Structure image: 

Aspergillus Species known to produce this metabolite: 

3d image file .c3d (requires Chem3d http://www.cambridgesoft.com/Ensemble_for_Chemistry/ChemBio3D/): 

jmol file (.mol) requires Java to run (http://www.java.com/en/download/help/enable_panel.xml): 


Date uploaded: 

2008-07-14 09:47:52